OncoMatch

OncoMatch/Gastric / Stomach Cancer/FGFR2

Gastric / Stomach CancerFGFR2 Clinical Trials

2 recruiting trials·Updated daily from ClinicalTrials.gov

FGFR2 amplification or fusion occurs in approximately 5–10% of gastric cancers and defines a targetable subgroup. Bemarituzumab, an FGFR2b-directed antibody, demonstrated survival benefit over chemotherapy in FGFR2b-overexpressing gastric cancer (FIGHT trial). Trials evaluate selective FGFR inhibitors (pemigatinib, futibatinib), FGFR2-directed ADCs, and combination strategies for FGFR2-amplified or overexpressing gastroesophageal adenocarcinoma.

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Other Gastric / Stomach Cancer biomarkers

Browse other molecular targets with active Gastric / Stomach Cancer trials.

HER2 (ERBB2)PD-L1 (CD274)MMR / MSI-H