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OncoMatch/Clinical Trials/NCT07840092

Biomarker Validation for Treatment Efficacy and Recurrence Prediction in Hepatocellular Carcinoma

Official title: Clinical Validation Study of Biomarkers for Predicting Treatment Efficacy in Patients With Hepatocellular Carcinoma Based on Prospective and Retrospective Clinical Samples

Is NCT07840092 recruiting? Yes, currently enrolling (Oct 2026).

RecruitingTianjin Medical University Cancer Institute and HospitalNCT07840092Data as of Oct 2026Location: China

Observational Model: Cohort Time Perspective: Other (prospective and retrospective data/sample collection) Primary Purpose: Other (biomarker validation for treatment response and recurrence prediction) Biospecimen Retention: Samples With DNA Biospecimen Description: Residual tissue, wax blocks/slides, residual puncture/surgical materials, and residual blood from routine testing; additional peripheral blood, 5-10 mL per collection, may be collected if needed after separate informed consent. Enrollment: 500 (anticipated) Study Population: Adult patients with HCC confirmed by imaging and/or pathology at participating centers, receiving standard antitumor therapy and planned for systematic follow-up. Sampling Method: Not specified in the protocol.

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Extracted eligibility criteria

Cancer type

Hepatocellular Carcinoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: liver transplantation

Lab requirements

Liver function

child-pugh class a or stable b; major organ function basically compensated

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07840092 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior liver transplantation disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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