OncoMatch

OncoMatch/Clinical Trials/NCT07831772

REMIND Maintenance Radiotherapy for Newly Diagnosed Glioblastoma

Official title: REMIND: An Investigator Initiated Study Testing the Feasibility of Maintenance Radiotherapy for Patients With Newly Diagnosed Glioblastoma

Is NCT07831772 recruiting? Yes, currently enrolling (Oct 2026). This NA trial studies non-drug interventions for glioblastoma.

NARecruitingUniversity of MinnesotaNCT07831772Data as of Oct 2026

REMIND is a single-center feasibility study testing maintenance radiotherapy in adult patients with newly diagnosed glioblastoma. Participants will be consented before starting standard-of-care concurrent temozolomide and radiotherapy. After enrollment, participants will enter an observational lead-in phase while receiving standard-of-care therapy off study. Approximately 4 weeks after temozolomide, participants will receive one study-specific 2 Gy fraction of maintenance radiotherapy directed at the post-operative cavity and areas of prior enhancing disease. The study will evaluate the safety and feasibility of delivering maintenance radiotherapy. Blood samples will also be collected before and after maintenance radiotherapy to descriptively compare myeloid-derived suppressor cell frequency.

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Extracted eligibility criteria

Cancer type

Glioblastoma

Prior therapy

Cannot have received: radiation therapy to the brain

Prior radiation therapy to the brain

Lab requirements

Blood counts

absolute neutrophil count at least 1.5 × 10^9/l, platelets at least 50 × 10^9/l, and hemoglobin at least 8 g/dl independent of transfusion within 14 days of screening

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Minnesota Radiation Oncology · Minneapolis, Minnesota

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT07831772 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior radiation therapy to the brain disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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Related pages

Glioblastoma trials