OncoMatch

OncoMatch/Clinical Trials/NCT07803289

Biomarkers for Cancer Treatment

Is NCT07803289 recruiting? Yes, currently enrolling (Sep 2026).

RecruitingUniversity Hospitals Coventry and Warwickshire NHS TrustNCT07803289Data as of Sep 2026Location: United Kingdom

Circulating biomarkers, such as miRNAs and proteomics, undergo identifiable and measurable changes during and following treatment for cancer, compared to pre-treatment baseline. Some of these changes may be associated either with known treatment parameters or predictive for cardiac or lung toxicity. The aim is to identify and validate changes following treatment for cancer, compared to pre-treatment baseline, as well as differential miRNA expression in two-group comparisons (patients receiving radical RT/chemoRT for thoracic cancers versus IO-based complex SACT).

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: chemotherapy

Use of chemotherapy or immunotherapy in the last 5 years. (Cohort 1)

Cannot have received: immunotherapy

Use of chemotherapy or immunotherapy in the last 5 years. (Cohort 1)

Cannot have received: radical radiation therapy or chemo-radiation therapy within the thorax

Use of radical RT or chemo-RT within the thorax in the last 5 years. (Cohort 2)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07803289 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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