OncoMatch

OncoMatch/Clinical Trials/NCT07785180

A Non-interventional Study of Participants With BPDCN Treated With Chemotherapy

Is NCT07785180 recruiting? Yes, currently enrolling (Sep 2026). Studying Chemotherapy for blastic plasmacytoid dendritic cell neoplasm (bpdcn).

RecruitingStemline Therapeutics, Inc.NCT07785180Data as of Sep 2026Location: International · 11 countries

Treatment: ChemotherapyThe main goal of this study is to investigate the effectiveness and safety of chemotherapy agents in the treatment of participants with BPDCN and to provide comparator arm data to the prospective ELZONRIS registry study (STML-401-0521).

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Extracted eligibility criteria

Treatments studied

Other

Chemotherapy

Biomarker criteria

Required: CD4 expression

demonstration of a specific immunophenotype (either by immunohistochemistry or flow cytometry), particularly CD4, CD56, and CD123

Required: CD56 expression

demonstration of a specific immunophenotype (either by immunohistochemistry or flow cytometry), particularly CD4, CD56, and CD123

Required: IL3RA expression

demonstration of a specific immunophenotype (either by immunohistochemistry or flow cytometry), particularly CD4, CD56, and CD123

Prior therapy

Min 0 prior lines

Must have received: chemotherapy — first-line treatment for BPDCN

treated with chemotherapy regimens (at a minimum) as first-line treatment for BPDCN from May 2016

Cannot have received: investigational agent

Participant has received an investigational agent as first-line therapy for BPDCN

Cannot have received: first-line therapy for BPDCN in an interventional clinical trial

Participant has received first-line therapy for BPDCN in an interventional clinical trial

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07785180 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior investigational agent, first-line therapy for BPDCN in an interventional clinical trial disqualifies patients from enrollment.

Does this trial require CD4?

Yes, CD4 expression is a required biomarker for enrollment.

Does this trial require CD56?

Yes, CD56 expression is a required biomarker for enrollment.

Does this trial require IL3RA?

Yes, IL3RA expression is a required biomarker for enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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