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OncoMatch/Clinical Trials/NCT07763197

Sample Collection for Ongoing Research and Product Evaluation Study - Non-muscle Invasive Bladder Cancer (SCORE-NMIBC)

Is NCT07763197 recruiting? Yes, currently enrolling (Sep 2026).

RecruitingNatera, Inc.NCT07763197Data as of Sep 2026

The SCORE-NMIBC study is a prospective, multi-center, study designed to collect data and biological samples from participants diagnosed with non-muscle Invasive Bladder Cancer (NMIBC). Study participants will undergo research blood and urine collections, as well as tumor tissue collected as part of a standard-of-care procedure(s), for use in research. Collected samples and data will be analyzed to evaluate biomarkers associated with development and validation of cancer monitoring and detection assays ("Natera cancer monitoring and detection test(s)").

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Extracted eligibility criteria

Cancer type

Urothelial Carcinoma

Disease stage

Required: Stage ≤T1

Excluded: Stage >T1

Grade: high grade

AUA/SUO risk stratification for primary non-muscle invasive bladder cancer; high grade T1; high grade TA; high grade prostatic urethral invasion

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: any cancer therapy

Exception: participants who have undergone surgical removal of basal or squamous skin cancers, as well as those who have received NMIBC-directed therapy, including those undergoing cystectomy for primary NMIBC or after recurrence/progression of NMIBC

Prior history and treatment for any cancer (including muscle invasive bladder cancer) within the past year, or if they have any other active cancer, with the exception of participants who have undergone surgical removal of basal or squamous skin cancers, as well as those who have received NMIBC-directed therapy, including those undergoing cystectomy for primary NMIBC or after recurrence/progression of NMIBC

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Natera, Inc. · Austin, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT07763197 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior any cancer therapy disqualifies patients from enrollment.

What disease stage is eligible?

Stage ≤T1 is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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