OncoMatch

OncoMatch/Clinical Trials/NCT07757490

Sonablate HIFU International Registry for PC & BPH Patients

Is NCT07757490 recruiting? Yes, currently enrolling (Sep 2026). Studying High Intensity Focused Ultrasound for localized prostate cancer.

RecruitingSonablateNCT07757490Data as of Sep 2026

Treatment: High Intensity Focused UltrasoundThe SONA FUSION Registry is an observational study designed to evaluate the long-term effectiveness and safety of the Sonablate High-Intensity Focused Ultrasound (HIFU) system. This study focuses on adult men who have been treated for localized prostate cancer, benign prostatic hyperplasia (BPH) with urinary symptoms, or a combination of both conditions. The registry collects real-world medical data from multiple clinics globally to better understand how well the HIFU treatment controls disease and affects urinary and sexual function over a 10- to 20-year period. The study includes two groups of participants: a retrospective group of patients who previously received treatment, and a prospective group of newly treated patients receiving standard clinical care. No experimental interventions are assigned for the purpose of this study. To protect participant privacy, all medical data is completely de-identified and stripped of direct identifiers before being securely transferred to the central coordinating center at Indiana University. The ultimate goal of this research is to improve patient care protocols, advance men's health knowledge, and establish evidence-based guidelines for minimally invasive prostate treatments.

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Extracted eligibility criteria

Treatments studied

Other

High Intensity Focused Ultrasound

Cancer type

Prostate Cancer

Disease stage

Required: Stage LOCALIZED

Excluded: Stage IV

localized prostate cancer

Demographics

Male only

Prior therapy

Must have received: Sonablate HIFU ablation

Having undergone Sonablate HIFU ablation as part of standard clinical care

Cannot have received: radical prostatectomy

Prior radical prostatectomy

Cannot have received: rectal wall surgery

Prior rectal wall surgery

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Indiana University Medical Center · Indianapolis, Indiana

Showing up to 5 US sites.

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Frequently asked questions

Is NCT07757490 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior radical prostatectomy, rectal wall surgery disqualifies patients from enrollment.

What disease stage is eligible?

Stage LOCALIZED is required.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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