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OncoMatch/Clinical Trials/NCT07750886

Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL)

Is NCT07750886 recruiting? Yes, currently enrolling (Sep 2026).

RecruitingNatera, Inc.NCT07750886Data as of Sep 2026

The SCORE-NHL study is a prospective, multi-center, study designed to collect data and biological samples from participants diagnosed with aggressive Stage I to IV non-Hodgkin Lymphoma (NHL). Study participants will undergo research blood collections of up to 60 mL as well as residual tissue collection, collected as part of a standard of care procedure, for use in research. Collected samples and data will be analyzed to evaluate biomarkers associated with development and validation of cancer monitoring and detection assays ("Natera cancer monitoring and detection test(s)").

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Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Diffuse Large B-Cell Lymphoma

Disease stage

Required: Stage I, II, III, IV

Grade: grade 3b

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: stem cell transplant

History of an allogeneic stem cell transplant or other organ transplant.

Cannot have received: organ transplant

History of an allogeneic stem cell transplant or other organ transplant.

Cannot have received: systemic anticancer therapy

Exception: participants who have undergone surgical removal of skin squamous cell or basal cell cancers

Prior history and treatment for any cancer within the past year or another active cancer, with the exception of participants who have undergone surgical removal of skin squamous cell or basal cell cancers.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Natera, Inc. · Austin, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT07750886 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage I or II or III or IV is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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