OncoMatch/Clinical Trials/NCT07711626
Foot Reflexology and Ta-VNS for Symptom Management in Head and Neck Cancer During CCRT
Is NCT07711626 recruiting? Yes, currently enrolling (Sep 2026). This NA trial studies multiple treatments including True ta-VNS and Sham ta-VNS for head and neck neoplasms.
Treatment: True ta-VNS · Sham ta-VNS — Head and neck cancer (HNC) patients undergoing concurrent chemoradiotherapy (CCRT) frequently experience pain, xerostomia, fatigue, sleep disturbance, and other treatment-related toxicities that impair quality of life and treatment adherence, with incomplete relief from current supportive care. This randomized, single-blind, sham-controlled trial evaluates whether foot reflexology (FR), transcutaneous auricular vagus nerve stimulation (ta-VNS), and auricular acupressure (AA) reduce pain, xerostomia, fatigue, sleep disturbance, and treatment-related symptoms in HNC patients receiving cisplatin-based CCRT, compared with usual care. Participants are randomized to a foot reflexology group, an auricular vagus nerve stimulation group (each with true and sham subgroups), or a usual-care control group, and are followed at baseline and weeks 1, 2, and 4.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Head and Neck Squamous Cell Carcinoma
Disease stage
Required: Stage II, III, IVA
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Demographics
Lab requirements
Blood counts
Severe bone-marrow suppression (WBC <2,000/µL or platelets <50,000/µL) [excluded]
Severe bone-marrow suppression (WBC <2,000/µL or platelets <50,000/µL); Cardiac pacemaker or other implanted electronic device, or other severe cardiovascular disease
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT07711626 currently recruiting?
Yes, this trial is currently recruiting patients.
What disease stage is eligible?
Stage II or III or IVA is required.
Is there an age limit?
Yes. Patients must be 75 years or younger and at least 30 years old.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages