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OncoMatch/Clinical Trials/NCT07710885

Futibatinib (TAS-120) in Patients With Advanced Biliary Tract Cancer

Is NCT07710885 recruiting? Yes, currently enrolling (Sep 2026). This Phase 3 trial studies multiple treatments for biliary tract cancer.

Phase 3RecruitingTaiho Pharmaceutical Co., Ltd.NCT07710885Data as of Sep 2026Location: International · 4 countries

Treatment: Futibatinib · Zimberelimab · Durvalumab · Pembrolizumab · Gemcitabine · CisplatinTo compare overall survival (OS) of patients in Futibatinib and Zimberelimab in Combination with Gemcitabine plus Cisplatin versus Durvalumab or Pembrolizumab in Combination with Gemcitabine plus Cisplatin for patients with first-line advanced biliary tract cancer

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Extracted eligibility criteria

Treatments studied

Immunotherapy

ZimberelimabDurvalumabPembrolizumab

Targeted therapy

Futibatinib

Chemotherapy

GemcitabineCisplatin

Cancer type

Cholangiocarcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Max 0 prior lines

Cannot have received: FGFR inhibitor (futibatinib)

Has prior Fibroblast Growth Factor Receptor (FGFR)-directed therapy including futibatinib

Cannot have received: immune checkpoint inhibitor (anti-PD-L1, anti-PD-1, anti-CTLA-4, anti-TIGIT)

Has prior treatment with an anti-Programmed Death Ligand 1 (PD-L1), anti-Programmed Cell Death Protein 1 (PD-1), anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4), anti-T-cell immunoreceptor with Ig and ITIM domains (TIGIT), or other immune checkpoint inhibitor (ICI) or agonist as monotherapy or in combination

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07710885 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior FGFR inhibitor, immune checkpoint inhibitor disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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