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OncoMatch/Clinical Trials/NCT07694986

Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMD

Is NCT07694986 recruiting? Yes, currently enrolling (Jul 2026). This Phase 2 trial studies multiple treatments including cDC1 Vaccine and Trastuzumab for breast cancer.

Phase 2RecruitingH. Lee Moffitt Cancer Center and Research InstituteNCT07694986Data as of Jul 2026

Treatment: cDC1 Vaccine · Trastuzumab · NivolumabThe purpose of this study is to learn about the effects of the study treatment, Dendritic Cell Vaccine (DCV), in combination with trastuzumab or nivolumab to confirm the highest dose of the study treatment that can be given safely to participants with Breast Cancer (BC) with Leptomeningeal Disease (LMD).

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Nivolumab

Targeted therapy

Trastuzumab

Other

cDC1 Vaccine

Cancer type

Breast Carcinoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Moffitt Cancer Center · Tampa, Florida

Showing up to 5 US sites.

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Frequently asked questions

Is NCT07694986 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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