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OncoMatch/Clinical Trials/NCT07684508

Adjuvant Moderately Hypofractionated Intensity-modulated Radiotherapy for Cervical Cancer

Is NCT07684508 recruiting? Yes, currently enrolling (Jul 2026). This NA trial studies non-drug interventions for hypofractionated radiotherapy.

NARecruitingManni HuangNCT07684508Data as of Jul 2026Location: China

To investigate the safety and efficacy of moderately hypofractionated intensity-modulated radiotherapy in the treatment of postoperative cervical cancer

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Extracted eligibility criteria

Cancer type

Cervical Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

ECOG performance status 0 or 1

Demographics

Ages ≤ 75
Female only

Prior therapy

Must have received: radical hysterectomy with pelvic lymph node dissection

Status post radical hysterectomy with pelvic lymph node dissection with or without para-aortic lymph node dissection, and postoperative radiotherapy initiated within 3 months

Must have received: postoperative radiotherapy

Status post radical hysterectomy with pelvic lymph node dissection with or without para-aortic lymph node dissection, and postoperative radiotherapy initiated within 3 months

Cannot have received: neoadjuvant therapy

History of neoadjuvant therapy prior to enrollment

Lab requirements

Blood counts

white blood cell (WBC) count ≥3.0×10⁹/L, neutrophil count (NEUT) ≥1.5×10⁹/L, platelet count (PLT) ≥80×10⁹/L, hemoglobin (Hb) ≥90 g/L

Kidney function

normal or serum creatinine (SCr) ≤1.5×ULN or creatinine clearance ≥50 ml/min

Liver function

total bilirubin (TBIL) ≤1.5×ULN, aspartate aminotransferase (AST) or alanine aminotransferase (ALT) ≤2.5×ULN

Bone marrow function: white blood cell (WBC) count ≥3.0×10⁹/L, neutrophil count (NEUT) ≥1.5×10⁹/L, platelet count (PLT) ≥80×10⁹/L, hemoglobin (Hb) ≥90 g/L; renal function: normal or serum creatinine (SCr) ≤1.5×upper limit of normal (ULN) or creatinine clearance ≥50 ml/min; hepatic function: total bilirubin (TBIL) ≤1.5×ULN, aspartate aminotransferase (AST) or alanine aminotransferase (ALT) ≤2.5×ULN

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07684508 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior neoadjuvant therapy disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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