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OncoMatch/Clinical Trials/NCT07672262

VA Consolidation in Intermediate-Risk AML

Is NCT07672262 recruiting? Yes, currently enrolling (Jul 2026). This Phase 2 trial studies multiple treatments including Venetoclax and Azacitidine and Cytarabine ± Anthracycline for acute myeloid leukemia.

Phase 2RecruitingThe First Affiliated Hospital of Soochow UniversityNCT07672262Data as of Jul 2026Location: China

Treatment: Venetoclax and Azacitidine · Cytarabine ± AnthracyclineThis clinical trial aims to compare the efficacy and safety of venetoclax-based consolidation therapy versus conventional consolidation chemotherapy (intermediate/high-dose cytarabine) in newly diagnosed adult patients with intermediate-risk acute myeloid leukemia (AML). Participants must have achieved complete remission (CR) or CR with incomplete hematologic recovery (CRi) after induction therapy with venetoclax and azacitidine and are planned to undergo allogeneic hematopoietic stem cell transplantation (allo-HSCT).

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Extracted eligibility criteria

Treatments studied

Other

Venetoclax and AzacitidineCytarabine ± Anthracycline

Cancer type

Acute Myeloid Leukemia

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: Venetoclax + Azacitidine induction therapy (venetoclax, azacitidine) — induction for AML

Achieved first complete remission (CR) or CR with incomplete hematologic recovery (CRi) after ≤ 2 cycles of Venetoclax + Azacitidine (VA) induction therapy

Lab requirements

Kidney function

creatinine clearance ≥ 50 ml/min

Liver function

ast and alt ≤ 3 × uln; total bilirubin ≤ 2 × uln

Cardiac function

lvef ≥ 50%

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07672262 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received Venetoclax + Azacitidine induction therapy.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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