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OncoMatch/Clinical Trials/NCT07646145

Disitamab Vedotin Plus Intravesical Mitomycin C in HER2-Expressing Intermediate- to High-Risk Non-Muscle-Invasive Bladder Cancer

Is NCT07646145 recruiting? Yes, currently enrolling (Sep 2026). This Phase 2 trial studies multiple treatments including Disitamab Vedotin and Mitomycin C (MMC) for non-muscle-invasive bladder cancer (nmibc).

Phase 2RecruitingShanxi Province Cancer HospitalNCT07646145Data as of Sep 2026Location: China

Treatment: Disitamab Vedotin · Mitomycin C (MMC)

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Disitamab Vedotin

Other

Mitomycin C (MMC)

Cancer type

Urothelial Carcinoma

Biomarker criteria

Required: HER2 (ERBB2) expression (ihc 1+, 2+ or 3+)

Prior therapy

Cannot have received: bladder radiotherapy for urothelial carcinoma

Received bladder radiotherapy for urothelial carcinoma before treatment

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07646145 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior bladder radiotherapy for urothelial carcinoma disqualifies patients from enrollment.

Does this trial require ERBB2?

Yes, ERBB2 expression is a required biomarker for enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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