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OncoMatch/Clinical Trials/NCT07645261

SBRT-LATTICE-PATHY

Is NCT07645261 recruiting? Yes, currently enrolling (Jul 2026). This Phase 2 trial studies non-drug interventions for cancer (advanced stage).

Phase 2RecruitingUniversity of Sao Paulo General HospitalNCT07645261Data as of Jul 2026Location: Brazil

To assess the importance of using SBRT-LATTICE-PATHY for the radiotherapy treatment of large tumors that would be considered intractable by currently used standard techniques. In this present study, the investigators will have the possibility of combining SBRT and LATTICE techniques, incorporating the concept of hypoxic tissue irradiation, which are potential modulators of abscopal and bystander effects, performing partial punctual treatment in the vertex region, without the need for irradiation of the entire tissue volume, further improving safety in relation to possible toxicities.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: local radiotherapy

previous local radiotherapy

Cannot have received: systemic therapy

ongoing systemic therapy

Lab requirements

Kidney function

renal insufficiency that prevents the use of iodinated contrast [excluded]

renal insufficiency that prevents the use of iodinated contrast [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07645261 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior local radiotherapy, systemic therapy disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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