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OncoMatch/Clinical Trials/NCT07638774

The Efficacy of Compression/Ice Gloves/Socks in Patients With UTD1-induced Neuropathy.

Is NCT07638774 recruiting? Yes, currently enrolling (Jul 2026). This NA trial studies multiple treatments including compression glove/sock and ice glove/sock for locally advanced or metastatic breast cancer.

NARecruitingFudan UniversityNCT07638774Data as of Jul 2026Location: China

Treatment: compression glove/sock · ice glove/sockThis study is a prospective, multicenter, phase Ⅲ trial to evaluate of the compression/ice gloves/socks efficacy in UTD1-induced peripheral sensory and motor neuropathy. 324 patients will be included. All patients will be randomly divided into three groups at a ratio of 1:1:1. Group A is the blank control group, group B is the compression glove/sock group, and group C is the ice glove/sock group.

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Extracted eligibility criteria

Treatments studied

Other

compression glove/sockice glove/sock

Cancer type

Breast Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75
Female only

Prior therapy

Cannot have received: utd1

Lab requirements

Blood counts

ANC ≥1,500/mm3; WBC ≥3.5×10^9/L; platelets ≥75,000/mm3; hemoglobin ≥9 g/dL; no blood transfusion and blood products within 14 days; no G-CSF and other hematopoietic stimulation factor within 7 days

Kidney function

Serum creatinine ≤1.5 × ULN

Liver function

AST, ALT, ALP ≤ 2.5 × ULN when no liver metastasis; ≤ 5 × ULN when liver metastasis

Adequate organ and bone marrow function defined as follows within 7 days before enrollment: ANC ≥1,500/mm3, WBC ≥3.5×10^9/L, platelets ≥75,000/mm3, hemoglobin ≥9 g/dL, no blood transfusion and blood products within 14 days, no G-CSF and other hematopoietic stimulation factor within 7 days. Serum creatinine ≤1.5 × ULN; AST, ALT, ALP ≤ 2.5 × ULN when no liver metastasis; ≤ 5 × ULN when liver metastasis.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07638774 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior utd1 disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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