OncoMatch

OncoMatch/Clinical Trials/NCT07629726

A Phase 1/2 Study of KK2430 in Participants With Hematologic Neoplasms

Is NCT07629726 recruiting? Yes, currently enrolling (Jul 2026). This Phase 1/2 trial studies KK2430 for hematologic neoplasms.

Phase 1/2RecruitingKyowa Kirin Co., Ltd.NCT07629726Data as of Jul 2026

Treatment: KK2430KK2430 ("Study Drug") as a potential treatment for people with Hematologic Neoplasms. KK2430 is an experimental drug; it has not been approved for the treatment of any disease by health authorities such as United States Food and Drug Administration (FDA), and this is the first time it will be given to people. The purpose of this Study is to find out more information about KK2430, whether it is safe in humans, how the body processes it, and if it works for treating your condition.

Check if I qualify

Extracted eligibility criteria

Treatments studied

Other

KK2430

Cancer type

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Non-Hodgkin Lymphoma

Multiple Myeloma

Myelodysplastic Syndrome

Chronic Lymphocytic Leukemia

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: allogenic transplant

History of prior allogenic transplant

Lab requirements

Blood counts

ANC, Platelets, Corrected serum calcium

Kidney function

Renal function values

Liver function

Meet laboratory values at Screening i.e., AST and ALT, Total bilirubin etc

Meet laboratory values at Screening i.e., ANC, Platelets, Corrected serum calcium, AST and ALT, Total bilirubin etc

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Prisma Health · Greenville, South Carolina

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT07629726 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior allogenic transplant disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify