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OncoMatch/Clinical Trials/NCT07627568

Analysis of Biomarkers in Patients With Acute Myeloid Leukemia After Allogeneic Stem Cell Transplantation Treated With Menin Inhibition.

Is NCT07627568 recruiting? Yes, currently enrolling (Jul 2026).

RecruitingUniversity of FreiburgNCT07627568Data as of Jul 2026Location: Germany

The white blood cells of patients with acute myeloid leukemia that have undergone allogeneic stem cell transplantation will be investigated. These are patient where the leukemia has returned after the transplantation.

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Extracted eligibility criteria

Cancer type

Acute Myeloid Leukemia

Biomarker criteria

Required: KMT2A (MLL) rearrangement

Required: NPM1 mutation

Prior therapy

Must have received: allogeneic stem cell transplant

Hematological relapse after allo-HCT

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07627568 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received allogeneic stem cell transplant.

Does this trial require KMT2A?

Yes, KMT2A rearrangement is a required biomarker for enrollment.

Does this trial require NPM1?

Yes, NPM1 mutation is a required biomarker for enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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