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OncoMatch/Clinical Trials/NCT07500701

Salvage Moderate Hypofractionated Versus Ultrahypofractionated Radiotherapy for Biochemical Recurrence After Radical Prostatectomy in Prostate Cancer

Is NCT07500701 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for prostate cancer.

Phase 3RecruitingSamsung Medical CenterNCT07500701Data as of May 2026

This study is the first prospective, randomized phase III clinical trial designed to evaluate whether ultrahypofractionated radiotherapy is non-inferior to conventionally moderately hypofractionated radiotherapy in terms of efficacy, with acceptable toxicity, in patients who develop biochemical recurrence following radical prostatectomy. Considering the potential clinical benefits of shorter treatment duration, cost reduction, and improved patient convenience, this study is expected to provide important evidence to optimize salvage radiotherapy strategies in routine clinical practice.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: radical prostatectomy

Patients who have undergone radical prostatectomy for prostate cancer

Cannot have received: pelvic radiotherapy

History of prior pelvic radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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