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OncoMatch/Clinical Trials/NCT07447050

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

Is NCT07447050 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Riluzole for breast cancer.

Phase 2RecruitingUniversity of California, IrvineNCT07447050Data as of Jun 2026

Treatment: RiluzoleThis is a phase II single-arm, Phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining efficacy of riluzole in preventing cognitive dysfunction in subjects with cancer, who are receiving chemotherapy.

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Extracted eligibility criteria

Treatments studied

Other

Riluzole

Cancer type

Breast Carcinoma

Sarcoma

Non-Small Cell Lung Carcinoma

Small Cell Lung Cancer

Head and Neck Squamous Cell Carcinoma

Colorectal Cancer

Ovarian Cancer

Hepatocellular Carcinoma

Renal Cell Carcinoma

Prostate Cancer

Urothelial Carcinoma

Testicular Germ Cell Tumor

Penile Carcinoma

Endometrial Cancer

Cervical Cancer

Lab requirements

Liver function

ast and/or alt < 3 x upper limit normal (uln)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Chao Family Comprehensive Cancer Center, University of California Irvine · Orange, California

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT07447050 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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