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OncoMatch/Clinical Trials/NCT07402915

Drug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Is NCT07402915 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies multiple treatments including AZD5335 and Itraconazole for fallopian tube cancer.

Phase 1RecruitingAstraZenecaNCT07402915Data as of Jun 2026Location: International · 4 countries

Treatment: AZD5335 · ItraconazoleThe purpose of this study is to assess the effect of itraconazole on the pharmacokinetics (PK) of AZ14170132.

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Extracted eligibility criteria

Treatments studied

Other

AZD5335Itraconazole

Cancer type

Ovarian Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Female only

Prior therapy

Min 1 prior line

Must have received: platinum-based chemotherapy

have received at least 1 prior line of platinum-containing chemotherapy and have progressed on or within 6 months after the date of the last dose of platinum

Must have received: VEGF inhibitor (bevacizumab)

must have received prior bevacizumab and/or Poly (ADP-ribose) polymerase (PARP) inhibitors according to local guidelines, unless ineligible

Must have received: PARP inhibitor

must have received prior bevacizumab and/or Poly (ADP-ribose) polymerase (PARP) inhibitors according to local guidelines, unless ineligible

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07402915 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received platinum-based chemotherapy and VEGF inhibitor.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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