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OncoMatch/Clinical Trials/NCT07363382

The Value of GRPR PET Imaging for Diagnosis and Staging in Prostate Cancer

Is NCT07363382 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including 68Ga-G21 and 68Ga-G23 for prostate cancer (adenocarcinoma).

Phase 1/2RecruitingFirst Affiliated Hospital of Fujian Medical UniversityNCT07363382Data as of Jun 2026Location: China

Treatment: 68Ga-G21 · 68Ga-G23The gastrin-releasing peptide receptor (GRPR) is highly expressed in prostate cancer (77%-100%). Numerous studies have confirmed that GRPR PET imaging has emerged as a significant molecular imaging modality in prostate cancer, particularly serving as a complementary tool to PSMA PET for addressing cases with negative or insufficient PSMA expression. It demonstrates substantial value in initial staging (especially in intermediate- and high-risk patients), detecting sites of biochemical recurrence, assessing metastatic lesions (notably in mCRPC), and guiding treatment decisions. 68Ga-G21 and 68Ga-G23 are two novel molecular probes targeting GRPR. This study aims to evaluate their biodistribution and diagnostic performance in prostate cancer and compare them with 68Ga-PSMA-11 PET imaging.

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Extracted eligibility criteria

Treatments studied

Other

68Ga-G2168Ga-G23

Cancer type

Prostate Cancer

Demographics

Ages ≤ 90
Male only

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07363382 currently recruiting?

Yes, this trial is currently recruiting patients.

Is there an age limit?

Yes. Patients must be 90 years or younger.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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