OncoMatch/Clinical Trials/NCT07319364
A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
Is NCT07319364 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies Fecal microbiota transplantation (FMT) for fecal microbiota transplantation (fmt).
Treatment: Fecal microbiota transplantation (FMT) — The goal of this clinical trial is to learn if fecal microbiota transplantation can treat in Gastrointestinal cancer patients with chemotherapy / targeted gastrointestinal symptoms. The main question it aims to answer is: To evaluate the effect of fecal microbiota transplantation (FMT) on gastrointestinal tract in patients with gastrointestinal tumors.
Check if I qualifyExtracted eligibility criteria
Biomarker criteria
Required: PD-L1 (CD274) any tested (testing required; no eligibility threshold specified)
Disease stage
Required: Stage IV
Metastatic disease required
Performance status
ECOG 1–3(Limited self-care)
Prior therapy
Must have received: chemotherapy
Planned to receive the 4th cycle of chemotherapy/targeted therapy
Must have received: targeted therapy
Planned to receive the 4th cycle of chemotherapy/targeted therapy
Lab requirements
Kidney function
sufficient organ function required; renal insufficiency or renal failure excluded
Liver function
sufficient organ function required; hepatic insufficiency or hepatic failure excluded
Cardiac function
sufficient organ function required; cardiac insufficiency or heart failure excluded
Laboratory test results during the screening period indicate that the subjects have sufficient organ function. Patients with major organ dysfunction or even failure, including but not limited to cardiac insufficiency or heart failure, renal insufficiency or renal failure, and hepatic insufficiency/hepatic failure [excluded]
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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