OncoMatch

OncoMatch/Clinical Trials/NCT07312630

Clinical Study of LV009 Injection for the Treatment of Relapsed/Refractory CD19-Positive Hematologic and Lymphoid Malignancies

Is NCT07312630 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies LV009 for non-hodgkin lymphoma (nhl).

Early Phase 1RecruitingPersonGen BioTherapeutics (Suzhou) Co., Ltd.NCT07312630Data as of May 2026

Treatment: LV009Evaluate the safety, pharmacokinetic (PK) characteristics, and pharmacodynamic (PD) characteristics of LV009 injection in subjects with relapsed/refractory CD19-positive hematologic malignancies.

Check if I qualify

Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Biomarker criteria

Required: CD19 positive

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received:

Meets the NCCN guidelines' criteria for recurrence/refractory disease

Lab requirements

Blood counts

Absolute lymphocyte count ≥ 0.5 × 10⁹/L; platelet count ≥ 50 × 10⁹/L; CD3-positive T cells ≥ 150 cells/μL

Kidney function

Kidney function meets requirements

Liver function

Liver function meets requirements

Cardiac function

Cardiopulmonary function meets requirements; exclusion of severe cardiac conditions including but not limited to: unstable angina, myocardial infarction (within 6 months prior to screening), congestive heart failure (NYHA class ≥ III), and severe arrhythmias

Liver and kidney function, as well as cardiopulmonary function, meet requirements. Absolute lymphocyte count ≥ 0.5 × 10⁹/L; platelet count ≥ 50 × 10⁹/L; CD3-positive T cells ≥ 150 cells/μL.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify