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OncoMatch/Clinical Trials/NCT07312188

A Study of F182112 in the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

Is NCT07312188 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including F182112+P and F182112+CD38 for relapsed or refractory multiple myeloma.

Phase 2RecruitingShandong New Time Pharmaceutical Co., LTDNCT07312188Data as of May 2026

Treatment: F182112+P · F182112+CD38This is a single - arm, multi - cohort, open - label, multi - center Phase II clinical study. It aims to evaluate the efficacy and safety of F182112 combined with different administration regimens in patients with relapsed or refractory multiple myeloma.

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: immunomodulatory agent (lenalidomide)

The previous treatment regimen must contain lenalidomide (lenalidomide must be used continuously for at least 2 cycles)

Must have received: proteasome inhibitor

The previous treatment regimen must contain...a proteasome inhibitor

Cannot have received: immunomodulatory agent (pomalidomide)

Participants whose previous treatment regimen contained pomalidomide or who were intolerant to pomalidomide cannot be enrolled.

Cannot have received: BCMA-targeted therapy

Patients who have previously received BCMA - targeted therapy.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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