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OncoMatch/Clinical Trials/NCT07308132

A Study of JNJ-95566692 in Participants With Non-Hodgkin Lymphoid Malignancies

Is NCT07308132 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies multiple treatments including JNJ-95566692 and JNJ-87801493 for lymphoma, non-hodgkin.

Phase 1RecruitingJanssen Research & Development, LLCNCT07308132Data as of May 2026

Treatment: JNJ-95566692 · JNJ-87801493The purpose of this study is to determine the putative recommended Phase 2 doses (RP2Ds) and optimal dose schedule(s) for JNJ-95566692 as a single agent (Arm A) and in combination with JNJ-87801493 (Arm B) (Part 1: Dose Escalation) and to further characterize the safety and clinical activity of JNJ-95566692 as a single agent (Arm A) and in combination with JNJ-87801493 (Arm B) at the putative RP2D(s) (Part 2: Dose Expansion).

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Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 2 prior lines

Must have received: αCD20 monoclonal antibody containing chemotherapy combination schedule

Participants must have received at least 2 prior lines of therapy including an αCD20 monoclonal antibody containing chemotherapy combination schedule

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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