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OncoMatch/Clinical Trials/NCT07308132

A Study of JNJ-95566692 in Participants With Non-Hodgkin Lymphoid Malignancies

Is NCT07308132 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies multiple treatments including JNJ-95566692 and JNJ-87801493 for lymphoma, non-hodgkin.

Phase 1RecruitingJanssen Research & Development, LLCNCT07308132Data as of Jun 2026Location: Australia · Belgium · Turkey (Türkiye)

Treatment: JNJ-95566692 · JNJ-87801493The purpose of this study is to determine the putative recommended Phase 2 doses (RP2Ds) and optimal dose schedule(s) for JNJ-95566692 as a single agent (Arm A) and in combination with JNJ-87801493 (Arm B) (Part 1: Dose Escalation) and to further characterize the safety and clinical activity of JNJ-95566692 as a single agent (Arm A) and in combination with JNJ-87801493 (Arm B) at the putative RP2D(s) (Part 2: Dose Expansion).

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Extracted eligibility criteria

Treatments studied

Other

JNJ-95566692JNJ-87801493

Cancer type

Non-Hodgkin Lymphoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 2 prior lines

Must have received: αCD20 monoclonal antibody containing chemotherapy combination schedule

Participants must have received at least 2 prior lines of therapy including an αCD20 monoclonal antibody containing chemotherapy combination schedule

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07308132 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received αCD20 monoclonal antibody containing chemotherapy combination schedule.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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