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OncoMatch/Clinical Trials/NCT07303894

A Study of Isoquercetin in People With Ovarian Cancer

Is NCT07303894 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Isoquercetin for ovarian cancer.

Phase 2RecruitingMemorial Sloan Kettering Cancer CenterNCT07303894Data as of May 2026

Treatment: Isoquercetin — The purpose of this study is to test whether isoquercetin can reduce markers in the blood that may indicate the risk of blood clots in people with ovarian cancer. The effects of isoquercetin will be compared with those of a placebo.

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Extracted eligibility criteria

Cancer type

Ovarian Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: chemotherapy — first-line

receiving first-line chemotherapy (day 1 of isoquercetin should align with day 1 of cycle 1 or 2 of chemotherapy) for neoadjuvant, adjuvant, or advanced settings

Lab requirements

Blood counts

Platelet count > 50,000/mcL; PT and PTT < 1.5 x institutional ULN

Kidney function

Estimated creatinine clearance (CrCl >30 ml/min)

Liver function

Total bilirubin < 3 x ULN without liver metastases and <5 x ULN in presence of liver metastases. AST and ALT < 3 x ULN without liver metastases and <5 x ULN in the presence of liver metastases.

Participants must have preserved organ and marrow function as defined below: Platelet count > 50,000/mcL; PT and PTT < 1.5 x institutional ULN; Total bilirubin < 3 x ULN without liver metastases and <5 x ULN in presence of liver metastases. AST and ALT < 3 x ULN without liver metastases and <5 x ULN in the presence of liver metastases. Estimated creatinine clearance (CrCl >30 ml/min)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Beth Israel Deaconess Medical Center (Data Collection Only) · Boston, Massachusetts
  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities) · Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth (All Protocol Activities) · Middletown, New Jersey
  • Memorial Sloan Kettering Bergen (All Protocol Activities) · Montvale, New Jersey
  • Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities ) · Commack, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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