OncoMatch

OncoMatch/Clinical Trials/NCT07302347

A Study of Pembrolizumab in Japanese Pediatric Participants With Solid Tumors or Lymphomas and Japanese Adult Participants With Merkel Cell Carcinoma (MK-3475-G21/KEYNOTE-G21)

Is NCT07302347 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies Pembrolizumab for malignant neoplasm.

Phase 1/2RecruitingMerck Sharp & Dohme LLCNCT07302347Data as of Jun 2026Location: Japan

Treatment: PembrolizumabResearchers are looking for new ways to treat people with solid tumors, lymphomas (blood cancers), and a certain type of skin cancer. The goals of this study are to learn: * About the safety of pembrolizumab (the study medicine) and if people tolerate it * What happens to different doses of pembrolizumab in a person's body over time * How the cancer responds (gets smaller or goes away) to treatment

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Pembrolizumab

Cancer type

Tumor Agnostic

Non-Hodgkin Lymphoma

Hodgkin Lymphoma

Disease stage

Required: Stage IIB, IIC, III, IV

Stage IIB, IIC, III or IV cutaneous melanoma; locally advanced (unresectable Stage III) or metastatic (Stage IV) melanoma; locally-advanced, or metastatic solid malignancy; metastatic MCC (Stage IV)

Demographics

Ages ≥ 0

Prior therapy

Must have received: surgery — adjuvant

surgically completely resected ... melanoma

Must have received: locoregional therapy (surgery and/or radiation therapy) — locoregional

MCC that has recurred following standard locoregional therapy with surgery and/or radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07302347 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received surgery and locoregional therapy (surgery and/or radiation therapy).

What disease stage is eligible?

Stage IIB or IIC or III or IV is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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