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OncoMatch/Clinical Trials/NCT07298642

Extended-field Proton Therapy for Cervical Cancer

Is NCT07298642 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies non-drug interventions for cervical cancer.

Phase 2/3RecruitingNational Taiwan University HospitalNCT07298642Data as of May 2026

Severe lymphopenia is a common complication of extended-field radiotherapy in cervical cancer, significantly impacting immune function and clinical outcomes. This study aims to evaluate whether proton therapy, with its superior dose distribution, can reduce lymphopenia and improve survival and toxicity profiles compared to photon therapy.

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Extracted eligibility criteria

Cancer type

Cervical Cancer

Disease stage

Required: Stage ≥ IIIC

stage ≥ IIIC

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: radiation therapy

Exception: pelvic or abdominal radiotherapy only

Prior history of pelvic or abdominal radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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