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OncoMatch/Clinical Trials/NCT07295262

NIR-II Fluorescence-Guided Hepatectomy Using ICG-Cisplatin Nanoprobes for HCC

Is NCT07295262 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies ICG-Cisplatin Nanoprobe (NIR-II NanoM) for liver cancer, adult.

Early Phase 1RecruitingWest China HospitalNCT07295262Data as of May 2026

Treatment: ICG-Cisplatin Nanoprobe (NIR-II NanoM)This prospective, single-arm exploratory study evaluates the feasibility and safety of a novel ICG-Cisplatin self-assembled nanoprobe (NIR-II NanoM) for fluorescence-guided surgery in patients with Hepatocellular Carcinoma (HCC). Participants will receive a transarterial injection of the nanoprobe mixed with lipiodol prior to surgery. During the subsequent laparoscopic anatomic hepatectomy, surgeons will utilize a Near-Infrared II (NIR-II) imaging system to visualize tumor boundaries and liver segments for precise resection.

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Extracted eligibility criteria

Cancer type

Hepatocellular Carcinoma

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Kidney function

Severe renal dysfunction excluded.

Liver function

Child-Pugh Class A liver function. Child-Pugh score > 7 excluded.

Cardiac function

Severe cardiac dysfunction excluded.

Child-Pugh Class A liver function. Child-Pugh score > 7 excluded. Severe cardiac, pulmonary, or renal dysfunction [excluded].

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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