OncoMatch

OncoMatch/Clinical Trials/NCT07295262

NIR-II Fluorescence-Guided Hepatectomy Using ICG-Cisplatin Nanoprobes for HCC

Is NCT07295262 recruiting? Yes, currently enrolling (Jun 2026). This Early Phase 1 trial studies ICG-Cisplatin Nanoprobe (NIR-II NanoM) for liver cancer, adult.

Early Phase 1RecruitingWest China HospitalNCT07295262Data as of Jun 2026Location: China

Treatment: ICG-Cisplatin Nanoprobe (NIR-II NanoM)This prospective, single-arm exploratory study evaluates the feasibility and safety of a novel ICG-Cisplatin self-assembled nanoprobe (NIR-II NanoM) for fluorescence-guided surgery in patients with Hepatocellular Carcinoma (HCC). Participants will receive a transarterial injection of the nanoprobe mixed with lipiodol prior to surgery. During the subsequent laparoscopic anatomic hepatectomy, surgeons will utilize a Near-Infrared II (NIR-II) imaging system to visualize tumor boundaries and liver segments for precise resection.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

ICG-Cisplatin Nanoprobe (NIR-II NanoM)

Cancer type

Hepatocellular Carcinoma

Demographics

Ages ≤ 75

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Kidney function

Severe renal dysfunction excluded.

Liver function

Child-Pugh Class A liver function. Child-Pugh score > 7 excluded.

Cardiac function

Severe cardiac dysfunction excluded.

Child-Pugh Class A liver function. Child-Pugh score > 7 excluded. Severe cardiac, pulmonary, or renal dysfunction [excluded].

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07295262 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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