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OncoMatch/Clinical Trials/NCT07281976

A Trial of LBL-024 Monotherapy or Combination Drug in Patients With Triple Negative Breast Cancer

Is NCT07281976 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including LBL-024 for and albumin-bound Paclitaxel for triple negative breast cancer.

Phase 1/2RecruitingNanjing Leads Biolabs Co.,LtdNCT07281976Data as of Jun 2026Location: China

Treatment: LBL-024 for · albumin-bound Paclitaxel · ToripalimabThis trial is an open-label, multicenter phase Ib/II clinical study to evaluate the efficacy and safety of LBL-024 monotherapy or in combination with albumin-bound paclitaxel in patients with recurrent or metastatic triple negative breast cancer(TNBC).

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Toripalimab

Chemotherapy

albumin-bound Paclitaxel

Other

LBL-024 for

Cancer type

Triple-Negative Breast Cancer

Breast Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: immunomodulatory drug

Use of immunomodulatory drugs within 2 weeks prior to first dose of study drug.

Cannot have received: live vaccination

Patients who received live vaccination within 4 weeks before the first dose of study drug or who are scheduled to receive live vaccination during the study treatment period and within 4 weeks after the last dose.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07281976 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior immunomodulatory drug, live vaccination disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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