OncoMatch/Clinical Trials/NCT07278557
Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia
Is NCT07278557 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies MRI sialography for head and neck cancer.
Treatment: MRI sialography — Radiation-induced xerostomia (dry mouth) is one of the most common and severe side effects for patients receiving radiation therapy for head and neck cancer. New approaches are needed to reduce this side effect and improve patients' quality of life after treatment. This is a Phase II, single-center, double-masked, parallel-arm, randomized controlled trial. It compares MRI-guided parotid ductal sparing to the standard approach of mean parotid gland sparing, focusing on patient-reported dry mouth outcomes in individuals receiving definitive radiotherapy for oropharyngeal cancer.
Check if I qualifyExtracted eligibility criteria
Cancer type
Head and Neck Squamous Cell Carcinoma
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Cannot have received: radiation therapy
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- University of North Carolina at Chapel Hill, Department of Radiation Oncology · Chapel Hill, North Carolina
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