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OncoMatch/Clinical Trials/NCT07276373

Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies

Is NCT07276373 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including Nenocorilant 200 mg and Nenocorilant 300 mg for neoplasms.

Phase 1/2RecruitingCorcept TherapeuticsNCT07276373Data as of May 2026

Treatment: Nenocorilant 200 mg · Nenocorilant 300 mg · Nenocorilant 400 mg · NivolumabThis open-label, dose-finding, and proof of concept study will evaluate the safety, tolerability, maximum-tolerated dose (MTD) and/or optimal dose of nenocorilant when administered in combination with nivolumab in patients with advanced solid malignancies.

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Extracted eligibility criteria

Performance status

ECOG 0–1(Restricted strenuous activity)

Lab requirements

Blood counts

adequate organ function

Kidney function

adequate organ function

Liver function

adequate organ function

Cardiac function

QTcF interval >450 msec, family history of long QT syndrome or unexplained sudden death at young age, or requirement for use of medication that may prolong the QTc interval [excluded]

Has adequate organ function; QTcF interval >450 msec, a family history of long QT syndrome or unexplained sudden death at young age, or a requirement for use of medication that may prolong the QTc interval

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Site 03 · Los Angeles, California
  • Site 01 · San Antonio, Texas
  • Site 02 · West Valley City, Utah

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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