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OncoMatch/Clinical Trials/NCT07266493

Efficacy and Safety of Neoadjuvant Envafolimab Combined With Albumin-bound Paclitaxel and Carboplatin for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

Is NCT07266493 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Chemotherapy (Albumin bound paclitaxel and Carboplatin) for esophageal squamous cell carcinoma.

Phase 2RecruitingShanghai Zhongshan HospitalNCT07266493Data as of Jun 2026Location: China

Treatment: Chemotherapy (Albumin bound paclitaxel and Carboplatin)This single center, prospective, single arm clinical study aims to evaluate the clinical efficacy and safety of Envafolimab combined with albumin bound paclitaxel and carboplatin as neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Chemotherapy (Albumin bound paclitaxel and Carboplatin)

Cancer type

Esophageal Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: immunotherapy

Cannot have received: chemotherapy

Cannot have received: targeted therapy

Cannot have received: radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07266493 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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