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OncoMatch/Clinical Trials/NCT07258511

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

Is NCT07258511 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments including JNJ-79635322 and Teclistamab for multiple myeloma.

Phase 3RecruitingJanssen Research & Development, LLCNCT07258511Data as of Jun 2026Location: International · 5 countries

Treatment: JNJ-79635322 · TeclistamabThe purpose of this study is to evaluate how well JNJ-79635322 works when compared with an anti-B-cell maturation antigen (BCMA)xCD3 bispecific antibody.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Teclistamab

Other

JNJ-79635322

Cancer type

Multiple Myeloma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 3 prior lines

Must have received: proteasome inhibitor

Must have received: immunomodulatory drug

Must have received: anti-cd38 antibody

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • USC Norris Comprehensive Cancer Center · Los Angeles, California
  • University of Connecticut Health Center · Farmington, Connecticut
  • Yale Cancer Center · New Haven, Connecticut
  • Florida Cancer Specialists & Research Institute · Fort Myers, Florida
  • Emory University · Atlanta, Georgia

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT07258511 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received proteasome inhibitor and immunomodulatory drug.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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