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OncoMatch/Clinical Trials/NCT07222267

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

Is NCT07222267 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies multiple treatments including BG-75202 and CDK4 Inhibitor for breast cancer.

Phase 1RecruitingBeOne MedicinesNCT07222267Data as of May 2026

Treatment: BG-75202 · CDK4 Inhibitor · Estrogen Receptor Antagonist · Aromatase InhibitorThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75202 (KAT6A/B inhibitor) alone and in combination with other therapies in participants with breast cancer and other advanced solid tumors.

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Extracted eligibility criteria

Cancer type

Breast Carcinoma

Tumor Agnostic

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: KAT6A/B or KAT7 inhibitor/degrader

Prior exposure to KAT6A/B or KAT7 inhibitors/degraders

Lab requirements

Blood counts

Kidney function

Liver function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Washington University in St Louis · St Louis, Missouri
  • Next Oncology Austin · Austin, Texas
  • The University of Texas Md Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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