OncoMatch/Clinical Trials/NCT07217704
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.
Is NCT07217704 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies [18F]FAPI-74 PET/CT for esophageal cancer.
Treatment: [18F]FAPI-74 PET/CT — This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of \[¹⁸F\]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically confirmed gastric, gastroesophageal junction or esophageal cancer. Following screening, using a standardized administration protocol and dose, participants will undergo \[¹⁸F\]FAPI-74 PET/CT screening. SOC procedures and interventions will be captured during 3 months +/-14 days post injection. The primary objective is to evaluate the sensitivity and specificity of such \[¹⁸F\]FAPI-74 PET/CT using a composite SOT panel. The maximum expected duration of the trial is approximately 24 months from first patient screening to last patient SOC follow up. The participants will be followed-up for safety for 24 to 72 hours after the dose of \[¹⁸F\]FAPI-74 PET/CT.
Check if I qualifyExtracted eligibility criteria
Cancer type
Esophageal Carcinoma
Gastric Cancer
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Cannot have received: treatment for curative intent of Gastroesophageal cancers
Treatment, including chemotherapy, radiation, immunotherapy or surgery for curative intent of Gastroesophageal cancers
Lab requirements
Kidney function
gfr < 30 ml/min [excluded]
Liver function
t. bili >1.5x uln or alk phos, alt, or ast >5x uln [excluded]
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Helios CR Inc./RadNet · Cerritos, California
- Hoag Memorial Hospital · Irvine, California
- UCLA · Los Angeles, California
- Moffit Cancer Center · Tampa, Florida
- Indiana University Health University Hospital · Indianapolis, Indiana
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify