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OncoMatch/Clinical Trials/NCT07217600

Ondansetron Orodispersible Film for Vomiting Prevention in Pediatric Radiotherapy

Is NCT07217600 recruiting? Yes, currently enrolling (May 2026). This Phase 4 trial studies multiple treatments including Ondansetron orodispersible film once and Ondansetron orodispersible film twice for radiotherapy-induced nausea and vomiting (rinv).

Phase 4RecruitingChongqing University Cancer HospitalNCT07217600Data as of May 2026

Treatment: Ondansetron orodispersible film once · Ondansetron orodispersible film twiceThe goal of this study is to evaluate the antiemetic efficacy and drug safety of ondansetron orodispersible film in pediatric patients with malignant tumors who received moderate emetic risk radiation induced vomiting, and to formulate reasonable and effective clinical medication regimen for preventing vomiting caused by moderate emetic risk radiation in children with malignant tumor.

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Extracted eligibility criteria

Lab requirements

Blood counts

ANC >= 1.0 × 10^9/L (after discontinuation of G-CSF), PLT >= 50 × 10^9/L (without drug support or transfusion therapy), HGB >= 80g/L

Kidney function

BUN and CRE <= 1.5x ULN

Liver function

total bilirubin <= 1.5x ULN, ALT <= 2.5x ULN, AST <= 2.5x ULN, alkaline phosphatase ≤ 1.5x ULN, serum albumin >= 2.5 g/dL

The blood routine test must meet the following criteria: ANC >= 1.0 × 10^9/L (after discontinuation of G-CSF), PLT >= 50 × 10^9/L (without drug support or transfusion therapy), HGB >= 80g/L; Biochemical tests must meet the following standards: total bilirubin <= 1.5 times ULN (upper limit of normal), ALT <= 2.5 times ULN, AST <= 2.5 times ULN, alkaline phosphatase ≤ 1.5 times ULN, serum albumin >= 2.5 g/dL, BUN and CRE <= 1.5 × ULN

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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