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OncoMatch/Clinical Trials/NCT07211659

Trial of THEO-260 (Administered Via Intraperitoneal Route) in Ovarian Cancer Patients

Is NCT07211659 recruiting? Yes, currently enrolling (Sep 2026). This Phase 1 trial studies THEO-260 for ovarian cancer.

Phase 1RecruitingTheolytics LimitedNCT07211659Data as of Sep 2026

Treatment: THEO-260A research study evaluating a new oncolytic virus, THEO-260, in patients with advanced ovarian cancer. The trial will investigate different doses of THEO-260 administered by the intraperitoneal route to identify a dose that is safe, well tolerated, and exhibits preliminary evidence of anti tumour activity.

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Extracted eligibility criteria

Treatments studied

Other

THEO-260

Cancer type

Ovarian Cancer

Performance status

ECOG 0–1(Restricted strenuous activity)

ECOG performance status of 0 or 1

Demographics

Female only

Prior therapy

Cannot have received: group B adenovirus

Prior treatment with a group B adenovirus

Lab requirements

Cardiac function

Left ventricular ejection fraction (LVEF) <45%, unstable angina, serious uncontrolled cardiac arrhythmia, a myocardial infarction within 6 months prior to trial enrolment or a history of myocarditis

Left ventricular ejection fraction (LVEF) <45%, unstable angina, serious uncontrolled cardiac arrhythmia, a myocardial infarction within 6 months prior to trial enrolment or a history of myocarditis

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT07211659 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior group B adenovirus disqualifies patients from enrollment.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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