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OncoMatch/Clinical Trials/NCT07203378

Nurturing Exercise Routine for Greater Improvement in Zest and Energy on Enhertu

Is NCT07203378 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for metastatic breast cancer.

Phase 2RecruitingUniversity of UtahNCT07203378Data as of May 2026

The goal of this study is to test the efficacy of using a 12-week, home-based, unsupervised aerobic and resistance training exercise program for changes in cancer-related fatigue in patients with metastatic breast cancer who are receiving Enhertu.

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Extracted eligibility criteria

Cancer type

Breast Carcinoma

Biomarker criteria

Allowed: HER2 (ERBB2) overexpression

Patients with High-Risk HER-2 + breast cancer after completion of neoadjuvant chemotherapy requiring adjuvant Enhertu are allowed at the discretion of the treating physician.

Prior therapy

Must have received: antibody-drug conjugate (Enhertu)

Has received 3 or 4 cycles of Enhertu and is expected to continue treatment for at least 12 weeks.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Huntsman Cancer Institute at University of Utah · Salt Lake City, Utah

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