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OncoMatch/Clinical Trials/NCT07197554

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

Is NCT07197554 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies ST-01156 for advanced solid tumors.

Phase 1RecruitingSEED Therapeutics, Inc.NCT07197554Data as of May 2026

Treatment: ST-01156A Phase 1/1B Study of ST-01156 in Patients with Advanced Solid Malignancies

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Sarcoma

Hepatocellular Carcinoma

Cholangiocarcinoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: rbm39 inhibitor/degrader

Lab requirements

Blood counts

adequate organ function as defined in the protocol

Kidney function

adequate organ function as defined in the protocol

Liver function

adequate organ function as defined in the protocol

Has adequate organ function as defined in the protocol.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • The City of Hope National Medical Center · Duarte, California
  • Hoag Memorial Hospital · Newport Beach, California
  • Mass General Brigham Cancer Institute · Boston, Massachusetts
  • Dana Farber Cancer Institute · Boston, Massachusetts
  • Memorial Sloan Kettering Cancer Center · New York, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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