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OncoMatch/Clinical Trials/NCT07195916

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Is NCT07195916 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies INCA036873 for solid tumors.

Phase 1RecruitingIncyte CorporationNCT07195916Data as of May 2026

Treatment: INCA036873A study to evaluate the safety and tolerability of INCA036873 in participants with advanced solid tumors and hematological malignancies.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Non-Hodgkin Lymphoma

Multiple Myeloma

Myelodysplastic Syndrome

Chronic Lymphocytic Leukemia

Disease stage

Required: Stage ≥STAGE IIB (CTCL, MF OR SS WITH B0/B1 BLOOD INVOLVEMENT)

Measurable disease by RECIST v1.1 (ccRCC), Lugano 2014 (lymphomas), or ISCL/USCLC/EORTC (CTCL)

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received:

ccRCC: ≥1 prior line incl. ICI + TKI

Must have received:

DLBCL/HGBCL: ≥2 prior lines incl. immunochemotherapy and salvage

Must have received:

PTCL/CTCL: ≥1 prior systemic therapy

Cannot have received: CD70-targeting therapy

Prior CD70-targeting therapy, including CAR T

Cannot have received: CAR-T cell therapy

Exception: ≤12 weeks before enrollment

CAR T ≤12 weeks before enrollment

Cannot have received: autologous stem cell transplant

Exception: ≤12 weeks before enrollment

ASCT ≤12 weeks before enrollment

Cannot have received: organ transplant

prior organ or allogeneic transplant

Cannot have received: allogeneic transplant

prior organ or allogeneic transplant

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • City of Hope Medical Center · Duarte, California
  • University of California San Diego Medical Center, Moores Cancer Center · La Jolla, California
  • University of Michigan · Ann Arbor, Michigan
  • The University of Nebraska Medical Center · Omaha, Nebraska
  • Memorial Sloan Kettering Cancer Center · New York, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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