OncoMatch/Clinical Trials/NCT07195916
A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
Is NCT07195916 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies INCA036873 for solid tumors.
Treatment: INCA036873 — A study to evaluate the safety and tolerability of INCA036873 in participants with advanced solid tumors and hematological malignancies.
Check if I qualifyExtracted eligibility criteria
Cancer type
Tumor Agnostic
Acute Myeloid Leukemia
Acute Lymphoblastic Leukemia
Non-Hodgkin Lymphoma
Multiple Myeloma
Myelodysplastic Syndrome
Chronic Lymphocytic Leukemia
Disease stage
Required: Stage ≥STAGE IIB (CTCL, MF OR SS WITH B0/B1 BLOOD INVOLVEMENT)
Measurable disease by RECIST v1.1 (ccRCC), Lugano 2014 (lymphomas), or ISCL/USCLC/EORTC (CTCL)
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Must have received:
ccRCC: ≥1 prior line incl. ICI + TKI
Must have received:
DLBCL/HGBCL: ≥2 prior lines incl. immunochemotherapy and salvage
Must have received:
PTCL/CTCL: ≥1 prior systemic therapy
Cannot have received: CD70-targeting therapy
Prior CD70-targeting therapy, including CAR T
Cannot have received: CAR-T cell therapy
Exception: ≤12 weeks before enrollment
CAR T ≤12 weeks before enrollment
Cannot have received: autologous stem cell transplant
Exception: ≤12 weeks before enrollment
ASCT ≤12 weeks before enrollment
Cannot have received: organ transplant
prior organ or allogeneic transplant
Cannot have received: allogeneic transplant
prior organ or allogeneic transplant
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- City of Hope Medical Center · Duarte, California
- University of California San Diego Medical Center, Moores Cancer Center · La Jolla, California
- University of Michigan · Ann Arbor, Michigan
- The University of Nebraska Medical Center · Omaha, Nebraska
- Memorial Sloan Kettering Cancer Center · New York, New York
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify