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OncoMatch/Clinical Trials/NCT07193511

BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

Is NCT07193511 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including AVZO-103 and Combination Agent for solid tumor cancer.

Phase 1/2RecruitingAvenzo Therapeutics, Inc.NCT07193511Data as of Jun 2026

Treatment: AVZO-103 · Combination AgentThis study, the first clinical trial of AVZO-103, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor activity of AVZO-103 when administered intravenously as a monotherapy and in combination therapy to patients with locally advanced or metastatic urothelial cancer or other solid tumors.

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Extracted eligibility criteria

Treatments studied

Other

AVZO-103Combination Agent

Cancer type

Tumor Agnostic

Urothelial Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Avenzo Therapeutics Recruiting Site · Orlando, Florida
  • Avenzo Therapeutics Recruiting Site · Boston, Massachusetts
  • Avenzo Therapeutics Recruiting Site · Myrtle Beach, South Carolina
  • Avenzo Therapeutics Recruiting Site · Nashville, Tennessee
  • Avenzo Therapeutics Recruiting Site · Austin, Texas

Showing up to 5 US sites.

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Frequently asked questions

Is NCT07193511 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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