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OncoMatch/Clinical Trials/NCT07193511

BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

Is NCT07193511 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including AVZO-103 and Combination Agent for solid tumor cancer.

Phase 1/2RecruitingAvenzo Therapeutics, Inc.NCT07193511Data as of May 2026

Treatment: AVZO-103 · Combination AgentThis study, the first clinical trial of AVZO-103, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor activity of AVZO-103 when administered intravenously as a monotherapy and in combination therapy to patients with locally advanced or metastatic urothelial cancer or other solid tumors.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Urothelial Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Avenzo Therapeutics Recruiting Site · Orlando, Florida
  • Avenzo Therapeutics Recruiting Site · Boston, Massachusetts
  • Avenzo Therapeutics Recruiting Site · Myrtle Beach, South Carolina
  • Avenzo Therapeutics Recruiting Site · Nashville, Tennessee
  • Avenzo Therapeutics Recruiting Site · Austin, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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