OncoMatch/Clinical Trials/NCT07172802
A Study of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors
Is NCT07172802 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies GI-108 for advanced solid tumor.
Treatment: GI-108 — The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and therapeutic activity of GI-108, as a single agent, in patients with advanced or metastatic solid tumors
Check if I qualifyExtracted eligibility criteria
Cancer type
Tumor Agnostic
Non-Small Cell Lung Carcinoma
Head and Neck Squamous Cell Carcinoma
Pancreatic Cancer
Renal Cell Carcinoma
Disease stage
Metastatic disease required
Measurable disease as per RECIST v1.1.
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Cannot have received: immunotherapy related to mode of action of gi-102
Lab requirements
Blood counts
adequate organ and marrow function as defined in protocol
Kidney function
adequate organ and marrow function as defined in protocol
Liver function
adequate organ and marrow function as defined in protocol
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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