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OncoMatch/Clinical Trials/NCT07138755

The Efficacy and Safety of the Combination of PD-1 With Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients

Is NCT07138755 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Experimental for nsclc.

Phase 2RecruitingThe Third Xiangya Hospital of Central South UniversityNCT07138755Data as of May 2026

Treatment: ExperimentalTo evaluate the Efficacy and Safety of the Combination of Sintilimab With Platinum-doublet Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Biomarker criteria

Required: ALK wild-type

Required: EGFR wild-type

Required: HER2 (ERBB2) wild-type

Required: MET wild-type

Required: ROS1 wild-type

Disease stage

Required: Stage III

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: systematic anti-tumor treatment

No previous systematic anti-tumor treatment or chest radiotherapy for NSCLC

Cannot have received: chest radiotherapy

No previous systematic anti-tumor treatment or chest radiotherapy for NSCLC

Cannot have received: thoracic radiotherapy

Previously received local treatments for tumor lesions such as thoracic radiotherapy and radiofrequency ablation

Cannot have received: radiofrequency ablation

Previously received local treatments for tumor lesions such as thoracic radiotherapy and radiofrequency ablation

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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