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OncoMatch/Clinical Trials/NCT07132918

HEARTS Trial for Thoracic Cancers

Is NCT07132918 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for non-small cell lung cancer (stage iii).

Phase 2RecruitingUniversity of Wisconsin, MadisonNCT07132918Data as of May 2026

The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is whether MRgART affects the heart differently than LINAC. Participants will: * Receive radiation therapy * Undergo MRIs and bloodwork * Complete quality of life questionnaires

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Esophageal Carcinoma

Disease stage

Required: Stage IIB, IIIA, IIIB, IIIC, IV, I, II, III (AJCC 8th edition)

Stage IIB, IIIA, IIIB, IIIC, or IV non-operable non-small cell lung cancer; Limited stage small cell lung cancer; Stage I-III N0-2 disease esophageal/esophagogastric cancer; Stage II or III thymoma/thymic carcinoma

Prior therapy

Cannot have received: radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Wisconsin - Madison · Madison, Wisconsin

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