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OncoMatch/Clinical Trials/NCT07120282

Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I NSCLC

Is NCT07120282 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Tislelizumab 400 mg iv, q6w, for up to 1 year for pts in intervention group for lung cancer (nsclc).

Phase 2RecruitingCancer Institute and Hospital, Chinese Academy of Medical SciencesNCT07120282Data as of May 2026

Treatment: Tislelizumab 400 mg iv, q6w, for up to 1 year for pts in intervention groupA Randomized, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I NSCLC

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Biomarker criteria

Required: EGFR wild-type

No EGFR/ALK sensitive mutations

Required: ALK wild-type

No EGFR/ALK sensitive mutations

Required: PD-L1 (CD274) expression ≥1% (≥1%)

PD-L1 expression >=1%

Disease stage

Required: Stage I (AJCC 9th edition)

stage I non - small cell lung cancer (AJCC 9th edition), with tumor size 2cm <= T <=4cm

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: systemic anti-tumour therapy

Any previous treatment for current lung cancer, including radiotherapy and systemic anti-tumour therapies (chemotherapy, immunotherapy, targeted therapy, anti-angiogenesis therapy, etc.)

Cannot have received: chest radiotherapy

Prior chest radiotherapy (including lung, oesophageal, mediastinal, or breast cancer)

Lab requirements

Blood counts

Kidney function

Liver function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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