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OncoMatch/Clinical Trials/NCT07117890

Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations

Is NCT07117890 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including sunvozertinib 300mg and sunvozertinib 200mg for non small cell lung cancer.

Phase 2RecruitingFudan UniversityNCT07117890Data as of Jun 2026Location: China

Treatment: sunvozertinib 300mg · sunvozertinib 200mgThis study is a single arm study to access the anti-tumor efficacy and safety of sunvozertinib in untreated advanced NSCLC patients with EGFR uncommon mutations.

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Extracted eligibility criteria

Treatments studied

Other

sunvozertinib 300mgsunvozertinib 200mg

Cancer type

Non-Small Cell Lung Carcinoma

Biomarker criteria

Required: EGFR uncommon mutation (excluding 19del, L858R, T790M, Ex 20ins)

documented EGFR uncommon mutations from a local laoratory. at least one EGFR uncommon mutation (excluding EGFR 19del/l858r/T790m/Ex 20ins ) or compund mutations with EGFR uncommon mutations.

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: systemic anti-tumor therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07117890 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Does this trial require EGFR?

Yes, EGFR uncommon mutation (excluding 19del, L858R, T790M, Ex 20ins) is a required biomarker for enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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