OncoMatch

OncoMatch/Clinical Trials/NCT07081022

JS203 Combination Regimens in B-Cell Non-Hodgkin's Lymphoma

Is NCT07081022 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including JS203 in combination with gemcitabine and oxaliplatin and JS203 in combination with ifosfamide, carboplatin and etoposide for b-cell non-hodgkin's lymphoma.

Phase 2RecruitingShanghai Junshi Bioscience Co., Ltd.NCT07081022Data as of May 2026

Treatment: JS203 in combination with gemcitabine and oxaliplatin · JS203 in combination with ifosfamide, carboplatin and etoposide · JS203 in combination with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone · JS203 combined with lenalidomideTo evaluate the preliminary efficacy of JS203 combined with standard regimens in patients with B-cell Non-Hodgkin's lymphoma

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Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Biomarker criteria

Required: CD20 overexpression

B-cell non-Hodgkin's lymphoma expressing CD20 antigen

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: CD20-CD3 bispecific antibody

Previously received CD20-CD3 bispecific antibody treatment

Cannot have received: allogeneic hematopoietic stem cell transplantation

Previous allogeneic hematopoietic stem cell transplantation

Cannot have received: solid organ transplantation

Previous solid organ transplantation

Lab requirements

Blood counts

Kidney function

Liver function

Acceptable organ function at screening

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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