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OncoMatch/Clinical Trials/NCT07079423

Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis

Is NCT07079423 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Teclistamab (Tec) for al amyloidosis.

Phase 2RecruitingPeking Union Medical College HospitalNCT07079423Data as of May 2026

Treatment: Teclistamab (Tec)This is a phase II study in patients with newly diagnosed Mayo stage IIIB immunoglobulin light-chain (AL) Amyloidosis to evaluate the efficacy and safety of teclistamab

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Disease stage

Required: Stage IIIB

Lab requirements

Blood counts

neutrophil ≥ 1×10E9/L, hemoglobin ≥ 8g/dL, platelet ≥ 75×10E9/L

Kidney function

estimated glomerular filtration rate ≥ 20 mL/min, not receiving renal replacement therapy

Liver function

ALT or AST ≤ 5 × ULN, total bilirubin ≤ 2 × ULN

Neutrophil <1×10E9/L, hemoglobin < 8g/dL, or platelet < 75×10E9/L. Severely compromised hepatic or renal function: ALT or AST > 5 × ULN, total bilirubin > 2 × ULN, estimated glomerular filtration rate < 20 mL/min, or receiving renal replacement therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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