OncoMatch

OncoMatch/Clinical Trials/NCT07079423

Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis

Is NCT07079423 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Teclistamab (Tec) for al amyloidosis.

Phase 2RecruitingPeking Union Medical College HospitalNCT07079423Data as of Jun 2026Location: China

Treatment: Teclistamab (Tec)This is a phase II study in patients with newly diagnosed Mayo stage IIIB immunoglobulin light-chain (AL) Amyloidosis to evaluate the efficacy and safety of teclistamab

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Extracted eligibility criteria

Treatments studied

Other

Teclistamab (Tec)

Cancer type

Multiple Myeloma

Disease stage

Required: Stage IIIB

Lab requirements

Blood counts

neutrophil ≥ 1×10E9/L, hemoglobin ≥ 8g/dL, platelet ≥ 75×10E9/L

Kidney function

estimated glomerular filtration rate ≥ 20 mL/min, not receiving renal replacement therapy

Liver function

ALT or AST ≤ 5 × ULN, total bilirubin ≤ 2 × ULN

Neutrophil <1×10E9/L, hemoglobin < 8g/dL, or platelet < 75×10E9/L. Severely compromised hepatic or renal function: ALT or AST > 5 × ULN, total bilirubin > 2 × ULN, estimated glomerular filtration rate < 20 mL/min, or receiving renal replacement therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT07079423 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage IIIB is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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